Non-toxic melanoma therapy by a novel tubulin-binding agent
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چکیده
منابع مشابه
Vascular-targeting activity of ZD6126, a novel tubulin-binding agent.
The tubulin-binding agent ZD6126 is a novel vascular-targeting agent in clinical development for the treatment of solid tumors. In vivo, ZD6126 is rapidly converted into N-acetylcolchinol (ZD6126 phenol). In this study, we have explored the antivascular property of N-acetylcolchinol in vitro and ZD6126 in vivo. In cell culture, N-acetylcolchinol induced rapid changes in the morphology of human ...
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 2010
ISSN: 0020-7136,1097-0215
DOI: 10.1002/ijc.24765